Background

Established in 1973, the USC Laboratory of Applied Pharmacokinetics continues to develop improved methods for the optimal study and control of pharmacokinetic systems. These methods are designed for optimal analysis of drug behavior and optimal care of patients through optimal stochastic control of their drug therapy. The laboratory is supported by NIH grants GM068968 and EB005803, and by the Stella Slutzky Kunin Memorial Research Fund.

The laboratory is concerned with mathematical and statistical modeling of drug behavior, as well as with clinical testing and evaluation of new methods for optimizing drug therapy. The core of this multidisciplinary activity contains physicians, pharmacist, and mathematicians. The laboratory has special strengths in optimal stochastic control, optimal design of pharmacokinetic experiments and clinical trials, and with their practical application of tools for optimal clinical therapy.

The laboratory also seeks collaborative relationships to further the understanding and development of this field of Clinical Pharmacology. These collaborations may take the form of clinical trials and evaluations of therapeutic methods, or of development and software implementation of new concepts. Educational opportunities in the form of workshops and Fellowships are available to physicians, pharmacists, engineers, mathematicians, and other investigators. Fellowship applications in Clinical Pharmacology and Clinical Pharmacy are encouraged.